Tirzepatide vs. Semaglutide: A Research-Use Only Comparison

At The Peptide Company, we provide high-quality compounds for research professionals exploring some of the most cutting-edge developments in peptide science. Two peptides receiving significant attention in recent studies are Tirzepatide and Semaglutide.

DISCLAIMER: These peptides are not approved by the FDA for human consumption or therapeutic use. All

compounds sold by The Peptide Company are strictly for laboratory research only.

Overview of Tirzepatide

Tirzepatide is a synthetic peptide under investigation for its activity as a dual GIP and GLP-1 receptor

agonist. Researchers are interested in its potential effects on metabolic signaling pathways, including glucose regulation and energy balance.

Key Research Points:

• Targets GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 receptors

• Studied for its role in regulating appetite and insulin response

• Explored in research settings for its possible impact on body composition

.

Overview of Semaglutide

Semaglutide is a GLP-1 receptor agonist that has been widely studied in preclinical and clinical settings. It is often used as a reference peptide in experiments focusing on glucose metabolism and satiety signaling.

Key Research Points:

• Selectively activates the GLP-1 receptor

• Commonly studied in research related to appetite modulation and glycemic response

• Frequently compared to other incretin-based compounds

Side-by-Side (Research Use Only) Comparison

Feature	Tirzepatide	Semaglutide
Receptor Targets	GLP-1 + GIP	GLP-1 Only
Investigated For	Energy Balance, Metabolism	Appetite, Glucose Response
Dosing in Studies	2.5 - 15 mg/week (Titrated)	0.25 - 2.4 mg/week (Titrated)
Structure Type	Synthetic Peptide	Synthetic Peptide
Storage Recommendation	Refrigerated (35.6 - 46.4 F)	Refrigerated (35.6 - 46.4 F)

*These values are provided solely for educational reference based on published research and are not intended as usage guidelines.

Final Notes for Researchers

Both Tirzepatide and Semaglutide offer exciting potential in laboratory settings focused on metabolic

signaling and energy regulation. However, it's important to emphasize:

• These compounds are not approved for human use

• They are sold strictly for research and laboratory use

• Researchers should follow all safety, storage, and handling protocols